Technology area

Diagnostic imaging

815 funded awards, $557.2M total, FY2023-FY2025.

Data current as of 2026-05-11

Pattern read

Diagnostic imaging is heavily NCI-weighted (193 records). Oncology imaging for screening, staging, and treatment response is the dominant use case. NIA follows at 86 (mostly dementia imaging biomarkers) and NHLBI at 81 (cardiac and pulmonary imaging). Median award is $680K, on the higher side, consistent with the capital cost of imaging-system development. Concentration is low at 4.3%. The R41 share is significant at 102; imaging startups often originate in academic medical centers and retain those ties. The 454 R44 records and 189 R43 records show the typical pipeline: many Phase I winners did move to Phase II within the window.

Fit indicators

  • NCI dominant; oncology imaging is the canonical lane.
  • Strong STTR participation (R41 at 102). AMC-spinout structures are well-represented.

Watchouts

  • Imaging-system hardware tends to require strong device experience on the team. Regulatory pathway clarity is usually a reviewer focus.
  • Median $680K reflects the higher cost of imaging trials. Do not budget at therapeutic Phase I levels.

Where the money sat, by Institute / Center

IC funding decisions are set by portfolio priorities, NOFO scope, and program-officer judgment. These are funded records, not predictions of future funding.

ICNameRecordsMedian award
CA (NCI) National Cancer Institute 193 $885,000
AG (NIA) National Institute on Aging 86 $814,031
HL (NHLBI) National Heart Lung and Blood Institute 81 $476,329
NS (NINDS) National Institute of Neurological Disorders and Stroke 63 $408,192
MH (NIMH) National Institute of Mental Health 61 $910,446
GM (NIGMS) National Institute of General Medical Sciences 53 $500,000
DK (NIDDK) National Institute of Diabetes and Digestive and Kidney Diseases 50 $748,583
EY (NEI) National Eye Institute 40 $522,708
EB (NIBIB) National Institute of Biomedical Imaging and Bioengineering 39 $811,503
AI (NIAID) National Institute of Allergy and Infectious Diseases 33 $494,340
AR (NIAMS) National Institute of Arthritis and Musculoskeletal and Skin Diseases 29 $314,363
DE (NIDCR) National Institute of Dental and Craniofacial Research 21 $619,347
HD (NICHD) Eunice Kennedy Shriver National Institute of Child Health and Human Development 14 $392,722
TR (NCATS) National Center for Advancing Translational Sciences 12 $435,106
OD NIH Office of the Director 7 $926,753
DC (NIDCD) National Institute on Deafness and Other Communication Disorders 7 $295,770
HG (NHGRI) National Human Genome Research Institute 6 $706,994
MD (NIMHD) National Institute on Minority Health and Health Disparities 6 $932,071
ES (NIEHS) National Institute of Environmental Health Sciences 6 $299,082
DA (NIDA) National Institute on Drug Abuse 6 $310,320
AA (NIAAA) National Institute on Alcohol Abuse and Alcoholism 1 $305,545
AT (NCCIH) National Center for Complementary and Integrative Health 1 $295,780

FOA / NOFO routes

Opportunity number prefixes: PA = Parent Announcement (broad, omnibus, multiple ICs), PAR = Parent with Special Review, PAS = Parent with set-aside funds, RFA = Request for Applications (targeted, single-IC, fixed budget). Status unknown means the pipeline has not verified whether the FOA is currently posting awards; the SBIR omnibus has been in reauthorization gap during this window. See the glossary for full definitions.

OpportunityStatusRecords
PA-22-176 unknown 157
PA-23-230 unknown 115
PA-21-259 unknown 92
PA-22-178 unknown 56
PA-24-245 unknown 55
PA-23-232 unknown 42
PA-20-260 unknown 30
PAS-22-196 unknown 21
PA-24-247 unknown 21
PA-21-262 unknown 20
PA-23-231 unknown 18
PA-22-177 unknown 17
PA-21-260 unknown 14
PAS-19-316 unknown 13
PA-20-272 unknown 11
PA-20-262 unknown 9
PA-21-345 unknown 9
PA-24-246 unknown 8
PA-23-233 unknown 7
PAR-22-073 unknown 7
PAS-22-197 unknown 5
RFA-CA-22-025 unknown 5
PA-20-265 unknown 5
PAR-21-225 unknown 4
PA-18-871 unknown 4
PA-19-272 unknown 4
RFA-NS-20-010 unknown 3
PAR-24-131 expired 3
RFA-MD-23-003 unknown 3
PA-20-047 unknown 3
RFA-NS-20-011 unknown 3
PAR-21-266 unknown 2
PA-25-212 unknown 2
PA-18-574 unknown 2
RFA-CA-21-036 unknown 2
PAR-21-030 unknown 2
RFA-NS-23-006 unknown 2
PA-19-022 unknown 2
PA-20-261 unknown 2
PAR-18-326 unknown 2
RFA-NS-23-007 unknown 2
PA-19-271 unknown 2
RFA-CA-21-001 unknown 2
PA-19-273 unknown 2
RFA-CA-20-033 unknown 2
PAR-23-032 unknown 2
PAR-24-044 expired 1
PAR-21-265 unknown 1
RFA-CA-24-023 unknown 1
PA-24-248 unknown 1
RFA-MD-24-006 unknown 1
RFA-ES-23-008 unknown 1
RFA-CA-23-034 unknown 1
PA-23-189 unknown 1
PAR-18-108 unknown 1
PAR-19-335 unknown 1
PA-18-819 unknown 1
PA-19-270 unknown 1
PA-18-870 unknown 1
RFA-CA-16-008 unknown 1
PAR-18-801 unknown 1
RFA-ES-20-016 unknown 1
PA-18-573 unknown 1
RFA-NS-20-009 unknown 1
PAS-19-317 unknown 1
PAR-21-114 unknown 1
RFA-AG-23-029 unknown 1

Comparable funded projects

ApplIDFYICTitleOrganizationAmount
10813104 2025 CA Sonodynamic therapy using MRI-guided focused ultrasound in combination with 5-aminolevulinic acid to treat recurrent glioblastoma multiforme SONALASENSE INC $796,215
10933403 2025 CA Development of a Wearable Fluorescence Imaging Device for IntraoperativeIdentification of Brain Tumors BIOPTICSTECHNOLOGY, LLC $962,779
10935988 2025 AR Engineered Biotherapeutic Agent for Treatment of Post-Traumatic Osteoarthritis PROVIZIGEN LLC $158,663
10951013 2025 MH Ultra-dense ceramic scintillator for BrainPET scanner RADIATION MONITORING DEVICES, INC. $905,751
10953826 2025 HL A non-invasive, automated platform for hemodynamic assessment of patients at risk of heart failure or pulmonary hypertension SENSYDIA CORPORATION $1,607,970
11001563 2025 TR Advancing emergency medicine training with remote stereoscopic livestream technology IMMERSIVE TECH, INC. $846,089
11003971 2025 MH Microscope system for large scale optical imaging of neuronal activity using kilohertz frame rates MICROBRIGHTFIELD, LLC $995,876
11006192 2025 DE CraniaMap: Joint Solution for Auto-Segmentation and Landmarking from CBCT Scans THER-AI LLC $306,633

Review panels that have appeared on these records

Panel names use NIH's Center for Scientific Review (CSR) format: a 2-4 letter study-section code plus a meeting-cycle number in parentheses (e.g. ISB (12) = Instrumentation and Systems Development, cycle 12). SBIR/STTR review groups are temporary, meeting-specific bodies. The names below describe panels that have appeared on the cited funded-project records, not where future applications get assigned. NIH assigns panels at the time of submission based on the application content.

Limitations

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