The Multi-Grant Strategy For Deep Tech Companies: A Comprehensive Guide

June 17, 2025

Deep tech companies often face long development timelines, high research costs, and significant technical risk. These challenges can make it difficult to rely on a single source of funding.

Unlike consumer tech startups that may raise venture capital early and often, deep tech founders frequently turn to non-dilutive funding—capital that does not require giving up equity. Federal and state grants, for example, can support early-stage R&D or help validate a novel technology.

However, most grants are limited in scope, duration, or budget. Relying on a single grant may leave critical gaps in funding, especially during transitions between research phases.

This is where a multi-grant strategy becomes relevant.

What is a multi-grant strategy?

A multi-grant strategy refers to a coordinated approach where companies pursue multiple grants from different sources to support various aspects of their technology development. Instead of relying on a single grant, companies plan how different funding opportunities can work together to support their entire development timeline.

This approach is particularly important for deep tech companies working on complex technologies like advanced materials, quantum computing, or biotech innovations that require extended development periods. These technologies often take 5-10 years to reach commercialization, compared to 1-3 years for conventional software startups.

In a multi-grant strategy, each grant targets specific milestones or components of the overall project. For example, one grant might fund early feasibility testing, while another supports prototype development, and a third focuses on customer validation or regulatory approval.

Why multiple grants matter for deep tech

Deep tech companies face unique funding challenges compared to conventional startups. Their technologies often require substantial upfront investment in research and development before generating revenue.

A single grant rarely covers the entire journey from concept to commercialization. Most federal grants last 6-24 months and focus on specific research questions or development milestones. This creates a mismatch between the funding timeline and the actual development needs of deep tech innovations.

By pursuing multiple grants, companies can extend their runway without diluting ownership. This approach allows them to validate their technology, gather data, and build prototypes before seeking equity investment. The result is often a stronger negotiating position with potential investors.

Benefits of a multi-grant approach:

Table: Single-Grant vs. Multi-Grant Approaches

Aspect Single-Grant Approach Multi-Grant Strategy
Funding Duration Limited to one grant cycle Extended across multiple grants
Project Coverage Narrow focus on one aspect Comprehensive support for various stages
Risk Level High if the grant is rejected Distributed across multiple applications
Equity Impact May require earlier equity rounds Can delay or reduce equity dilution

Key non-dilutive funding programs

Several government programs offer non-dilutive funding for deep tech companies. These programs support different stages of technology development and have varying requirements and award amounts.

SBIR and STTR programs

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs are among the largest sources of early-stage funding for deep tech companies in the United States.

These programs follow a phased approach:

The main difference between SBIR and STTR is that STTR requires collaboration with a research institution like a university or national laboratory.

Various federal agencies participate in these programs, including the National Science Foundation (NSF), Department of Defense (DoD), and National Institutes of Health (NIH). Each agency has its own focus areas and application processes.

Other federal and state programs

Beyond SBIR/STTR, numerous other funding sources support deep tech innovation:

Aligning grants with development stages

A successful multi-grant strategy matches funding sources to appropriate development stages. Different grants have requirements and expectations that align with specific phases of technology development.

Early feasibility and proof of concept

The earliest stage focuses on validating core scientific principles and establishing basic feasibility. Grants at this stage typically support:

Appropriate funding sources include SBIR/STTR Phase I grants, NSF seed grants, and university partnership programs. These programs typically require less preliminary data but emphasize scientific novelty and potential impact.

Applications at this stage should focus on the innovation's uniqueness, the scientific principles involved, and initial proof of concept data. Reviewers look for evidence that the core concept is sound and worthy of further exploratio

Prototype development and validation

Once basic feasibility is established, the next stage involves building working prototypes and validating performance under relevant conditions. Grants at this stage support:

SBIR/STTR Phase II grants, DOE demonstration projects, and industry consortium funding are well-suited for this stage. These programs expect significant progress from earlier work and focus on translating scientific principles into practical applications.

Applications should highlight preliminary results, technical milestones, and plans for addressing engineering challenges. Reviewers assess whether the technology can move beyond the lab and function in real-world settings.

Commercialization preparation

The final pre-market stage involves scaling up production, meeting regulatory requirements, and preparing for market entry. Grants at this stage support:

Commercialization-focused grants like NSF's Partnerships for Innovation, NIH commercialization readiness programs, and state economic development funds target this stage. These programs emphasize market readiness and commercial potential.

Applications should address scale-up challenges, customer adoption barriers, and competitive advantages. Reviewers evaluate whether the technology can transition from a validated prototype to a viable product.

Avoiding common pitfalls

Managing multiple grants introduces complexity that can lead to compliance issues, resource conflicts, and administrative burdens. Understanding these challenges helps companies navigate them effectively.

Project scope overlap

Each grant should fund distinct aspects of the overall technology development. Agencies prohibit "double-dipping" or using multiple grants to fund the same work.

To avoid this pitfall:

For example, one grant might focus on developing a core technology component, while another addresses integration with other systems, and a third explores specific applications or use cases.

Resource allocation challenges

Multiple grants can strain a company's human and physical resources if not managed carefully.

Effective resource management includes:

Companies often underestimate the administrative burden of managing multiple grants. Each grant requires regular reporting, financial tracking, and compliance monitoring.

Reporting and compliance

Each funding agency has unique reporting requirements and compliance standards. Failing to meet these obligations can jeopardize current and future funding.

Best practices include:

Building a commercialization roadmap

A multi-grant strategy works best when integrated into a broader commercialization plan. This ensures that each funded project contributes to the company's long-term goals.

Market validation alongside technical development

Technical development and market validation should proceed in parallel. Grants can support both aspects:

Many grant programs, particularly those focused on commercialization, require or encourage these activities. Including market validation in grant proposals demonstrates a clear path to impact.

Integration with equity funding

Non-dilutive grants and equity investment can complement each other. Grants reduce technical risk and extend runway, making the company more attractive to investors.

A well-designed funding strategy might use:

Each successful grant builds credibility and reduces risk for potential investors. Companies can often secure better terms and higher valuations after demonstrating technical progress through grant-funded work.

Where to find strategic support

Navigating the complex landscape of grant funding can be challenging, especially for first-time founders. Several resources can provide guidance and support:

Professional grant support services like Cada can help companies identify appropriate funding opportunities, develop compelling proposals, and manage grant portfolios. These services often increase success rates by leveraging experience with specific agencies and programs.

When evaluating support options, consider their track record with similar technologies, familiarity with relevant agencies, and approach to grant portfolio management.

FAQs about multi-grant strategies

How do I avoid duplication when applying for multiple grants?

Each grant application should target distinct aspects of your technology or different development phases, with clear documentation of how the projects complement rather than overlap with each other.

Can I apply for grants from different agencies simultaneously?

Yes, companies can apply to multiple agencies at the same time, as long as each application focuses on different aspects of the technology and clearly states other pending applications.

How do matching requirements work in a multi-grant strategy?

Some grants require companies to match a portion of the funding, which can come from company resources or other non-federal sources, but one federal grant cannot be used as a match for another.

What happens if development timelines shift between grants?

Most agencies allow reasonable adjustments to project timelines with proper notification and justification, but significant changes may require formal approval through a modification request.

How does previous grant success affect future applications?

Previous grant success generally improves chances for future awards by demonstrating technical progress and grant management capability, though each application is still evaluated on its individual merits.

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